Jaelion

Research

Methodology & Limitations

Transparency about how we select, position, and present testing categories.

How We Select Testing Categories

Jaelion selects testing categories based on three criteria: clinical relevance to whole-patient care practices, support from peer-reviewed literature or recognized health authority guidance, and practical applicability within a provider-directed workflow.

We reference peer-reviewed literature, federal health agency guidance from the Centers for Disease Control and Prevention (CDC), National Center for Complementary and Integrative Health (NCCIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), World Health Organization (WHO), and U.S. Environmental Protection Agency (EPA), as well as professional society guidelines from the American Gastroenterological Association (AGA), American College of Gastroenterology (ACG), and American Academy of Allergy, Asthma and Immunology (AAAAI) to support each category. We do not select categories based solely on commercial availability or market demand.

We also apply a consistent framing standard: every testing category is positioned as a support tool for clinical investigation, not as a standalone diagnostic shortcut or guaranteed clinical outcome.

Known Limitations

Testing Supports, Not Replaces, Clinical Judgment

No laboratory test replaces a thorough clinical history, physical examination, and professional assessment. Testing is one data point among many.

Results Require Clinical Interpretation

Results should always be interpreted within the broader clinical picture by a qualified provider. Jaelion does not provide clinical interpretation or treatment recommendations.

Not All Sensitivities Are Detectable

No single test can definitively diagnose all food sensitivities, nutrient deficiencies, or toxic exposures. Testing identifies patterns and data points, not definitive diagnoses.

Biomonitoring Data Adds Context, Not Causation

Detecting an environmental compound or element through biospecimen analysis does not itself establish that it is causing a patient's symptoms or disease. Biomonitoring data add important clinical context and inform the investigative process; they are one component of a comprehensive clinical picture.

Evidence Continues to Evolve

The scientific literature supporting advanced biospecimen testing continues to grow. Some testing categories are supported by decades of published research; others reflect an expanding and active area of clinical investigation. We reference current peer-reviewed literature and update our evidence base as the field advances.

Scope of Practice Applies

Providers must order and interpret testing within their licensed scope of practice. Jaelion does not determine what is within any individual provider's scope.

Our Commitment to Transparency

We publish our methodology openly because we believe that a credible testing partner should be transparent about how testing categories are selected, how evidence is evaluated, and where clinical judgment is essential to interpretation. Our evidence base spans peer-reviewed literature, federal health agency guidance, and professional society standards — and we update it as the science advances. If you have questions about our methodology or the research behind a specific testing category, we welcome direct provider conversations.